Table 3.
Hypertension (Safe in Pregnancy) |
Heart Failure (Safe in Pregnancy) |
Pulmonary Hypertension (Safe in Pregnancy) |
Arrhythmias (Safe in Pregnancy) |
Anticoagulants/ Antiplatelets (Safe in Pregnancy) |
Not safe or Limited Data in Pregnancy |
---|---|---|---|---|---|
B Oral alpha-methyl dopa * Hydrochlorothiazide * |
B Bumetanide Torsemide Metolazone Dobutamine |
B Sildenafil * Epoprostenol |
B Lidocaine * Sotalol |
B Enoxaparin * Argatroban Bivalirudin Fondaparinux Clopidogrel Prasugrel |
Not safe D DOACs Atenolol Amiodarone (Can be used as a last resort) ACE-Inhibitors * Aldosterone antagonists Angiotensin receptor blockers Statins Dronaderone Dofetilide Ivabradine |
C Labetalol * Clonidine Nifedipine * Amlodipine * Nitroglycerin Hydralazine * Isodorbide dinitrate Nitroprusside * Bisoprolol * |
C Furosemide * Carvedilol Metoprolol * Isosorbide dinitrate Nitroglycerin Norepinephrine Hydralazine * Dopamine |
C Iloprost Treprostinil |
C Flecainide * (F) Digoxin * (F) Metoprolol * Propranolol * Labetalol * Sotalol (F) Adenosine * Verapamil Procainamide Quinidine * Atropine |
C Unfractionated heparin * Aspirin (81 mg) * Ticagrelor |
|
D Warfarin * (Safe after first trimester until 36 weeks gestation) |
Limited Data Mexiletine Ibutilide Propafenone * Disopyramide Nadolol Diltiazem |
Former Food & Drug Administration ABCD categories along with the indications are listed. * Safe in lactation. (F) = Can be used for Fetal Tachycardia.