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. 2022 Jul 18;23(14):7906. doi: 10.3390/ijms23147906

Figure 2.

Figure 2

Figure 2

Chemical enrichment analyses using ChemRICH. HEPE: hydroxy eicosapentaenoic acid; ME/CFS: myalgic encephalomyelitis/chronic fatigue syndrome; sr-IBS: self-reported physician diagnosed irritable bowel syndrome. The length of the bar represents altered ratio for each metabolic cluster. A bar restricted to the left of the centered vertical line indicates a metabolic cluster that is lower in ME/CFS patients. A bar restricted to the right of the centered vertical line indicates a metabolic cluster that is higher in ME/CFS patients. A bar that crosses the vertical line indicates a metabolic cluster that is dysregulated in mixed directions. (A) All ME/CFS vs. controls. (B) Female ME/CFS vs. female controls. (C) ME/CFS without sr-IBS vs. controls without sr-IBS.