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. 2022 Jul 14;15(7):868. doi: 10.3390/ph15070868

Table 6.

Some other Australian plants and their compounds with anti-neoplastic activity.

Plant Active Compounds Effects References
Terminalia ferdinandiana Tannins, flavonoids: gallic acid, ellagic acid, lutein, hesperitin, kaempferol, luteolin, and quercetin Antiproliferative and proapoptotic activity in cancer cell lines. No toxicity to human dermal fibroblasts and shrimp Artemia franciscana bioassay. [348,349]
Tasmannia lanceolata Phenolic acids: coumaric acid, chlorogenic acid. Flavonoids:
quercetin, quercetin 3-rutinoside, and anthocyanin (cyanidin
3-rutinoside)
Cytotoxicity to different cancer cell models with non-significant effects on normal colon, stomach, and intestine cells. [350]
Davidsonia pruriens Anthocyanin compounds, flavanoids Significant cytotoxicity to a panel of cancer cell models and low toxicity in the Artemia nauplii bioassay. [351,352]
Elaeocarpus angustifolius Not identified Significant cytotoxicity to Hela and Caco-2 cell models and low toxicity in the Artemia nauplii bioassay. [352]
Pittosporum angustifolium Alcaloids, saponins Antiproliferative effects of 7 saponins with IC50 values in a range of 1.74–34.1 µM for MCF7, HaCaT, LN18, and 5637 cancer cells. [353]