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Multifaceted role of YTHDF1 in gastrointestinal cancers. YHTDF1-driven translation of m6A-modified gene targets has been shown to confer malignant phenotypes that are associated with cancer cell intrinsic properties (proliferation, metastasis, stemness and cell death) as well as its interaction with the tumor microenvironment (inflammation and immunity). Part of the figure is created with BioRender.com.
