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. 2022 Jul 13;23(14):7725. doi: 10.3390/ijms23147725

Table 2.

Host targets of NEL T3SS effectors.

Organism Effector Name Main Characterized Binding Partners
No Ubiquitination Shown Ubiquitination Shown
S. enterica SlrP ERdj3 Thioredoxin
SspH1 PKN1
SspH2 Profilins, filamin, SGT1 Nod1
S. flexneri IpaH1.4 HOIL-1L HOIP
IpaH2.5 HOIL-1L HOIP
IpaH4.5 Rab31 p65, TBK1, RPN13, NLRP3
IpaH7.8 Glomulin, GSDMB, GSDMD
IpaH9.8 Ste7, U2AF35, NEMO, GBP1, GBP2, GBP4
IpaHa TRAF2