Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 21;27(14):4648. doi: 10.3390/molecules27144648

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effects of MEL-B treatment on UVB-irradiated HaCaT cells. (A) HaCaT cells were irradiated with UVB (40 mJ/cm²) then treated with MEL-B (0, 2.5, 5, 10, 20 μg/mL) followed by 24-h culture. Relative expression levels of LOR, FLG, and TGM1 were decreased by UVB radiation. (B) Relative expression levels of LOR were increased after MEL-B incubation in dose dependent. (C) Upregulation of MEL-B treatment on expression levels of FLG protein. (D) Dose-dependent MEL-B effect on upregulation of TGM1 protein expression in UVB-irradiated HaCaT cells. GAPDH antibody was used as loading control. Values are expressed as means ± SD (n = 3). ## p < 0.01 vs. the control group (Ctrl); * p < 0.05, ** p < 0.01 vs. the UVB-irradiated (model) group.