Table 3. Latency to escape (s) and distance travelled (cm) in a radial arm water maze among HIV-1 Tat transgenic [Tat(+)] young adult and middle-aged male mice and age-matched non-Tat-expressing controls [Tat(−)].
Latency to Escape (s) | Young adult | Middle-aged | ||
Tat(−) n = 8–9 | Tat(+) n = 12 | Tat(−) n = 12 | Tat(+) n = 10 | |
Day 1 | 47 ± 6 | 36 ± 3 | 49 ± 6 | 37 ± 4 |
Day 2 | 49 ± 8 | 27 ± 2* | 35 ± 6 | 37 ± 4 |
Day 3 | 50 ± 5 | 25 ± 3^ | 31 ± 6^ | 33 ± 4^ |
Distance (cm) | ||||
Day 1 | 372 ± 31 | 386 ± 29 | 410 ± 30 | 387 ± 30 |
Day 2 | 318 ± 32 | 320 ± 27 | 334 ± 37 | 380 ± 31 |
Day 3 | 349 ± 48 | 271 ± 23 | 307 ± 29 | 298 ± 31 |
*indicates an effect for young adult Tat(+) mice to differ from young adult Tat(−) mice. ^indicates a difference from young adult Tat(−) controls. p < 0.05.