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In vivo efficacy of peptides in AITC-induced pain model. (A,C) Effect of pretreatment with peptides on time spent paw guarding within a 5 min interval after AITC injection. (B,D) Effect of peptides on development of paw edema after AITC injection (4 h). The results are presented as the mean ± SD, n = 6–8 for each group; *** p < 0.001; versus saline group (ANOVA followed by a Tukey’s test).
