Table 3.

Colony-forming unit of Candida albicans on skin (dermal mycosis) of rats after treatment with the TH-loaded SLN-based hydrogel.

Treatment	No. of Animals with Positive Culture/Total No. of Animals	Log CFU/Infected Sites
Control (Base formulation)	7/7	5.69 ± 0.45
TH solution in ethanol	6/7	4.01 ± 0.33
TH-loaded SLN-based hydrogel	2/7	2.23 ± 0.19 *,#
Conventional marketed formulation of TH	1/7	1.46 ± 0.15 **

* p < 0.05, ** p < 0.01 vs. control group; ^# p < 0.05 vs. group received TH solution in ethanol.