Table 2.
Clinical Characteristics of Patients Aged ≤18 years Hospitalized for COVID-19-related Indication, 2 December 2021–23 January 2022.
| COVID-19-Related Admission (N = 58) | |
|---|---|
| Disposition | |
| Any ICU stay, N (%) | 11 (19) |
| Length of stay, median days (IQR) | 3.2 (1.9, 4.7) |
| Discharged alive, N (%) | 57 (98) |
| Respiratory support, N (%) | |
| No oxygen support | 35 (60) |
| Nasal cannula or face mask | 9 (16) |
| Non-invasive positive pressure ventilation | 7 (12) |
| Invasive mechanical ventilation | 6 (10) |
| Treatment, N (%) | |
| Remdesivir | 19 (33) |
| Steroids, COVID-19 indication | 12 (21) |
| Steroids, non-COVID-19 indication | 13 (22) |
| Sotrovimab | 1 (2) |
| Primary diagnosis, N (%) | |
| Croup | 7 (12) |
| Other respiratory a | 21 (36) |
| Clinical monitoring b | 9 (16) |
| Exacerbation of underlying conditions c | 9 (16) |
| Neurologic d | 4 (7) |
| Other e | 8 (14) |
| Viral co-infection | |
| Viral co-infection f, N (%) | 12 (21) |
| Viral pathogen(s) detected (N) | |
| Adenovirus | 0 |
| Coronavirus 229E | 0 |
| Coronavirus HKU1 | 0 |
| Coronavirus NL63 | 0 |
| Coronavirus OC43 | 0 |
| Influenza A | 0 |
| Influenza B | 0 |
| Parainfluenza 1 | 0 |
| Parainfluenza 2 | 0 |
| Parainfluenza 3 | 1 |
| Parainfluenza 4 | 0 |
| Human metapneumovirus | 3 |
| Respiratory syncytial virus | 6 |
| Rhinovirus/enterovirus | 3 |
IQR, interquartile range. a Includes asthma exacerbations, pneumonia, bronchiolitis, and exacerbations of underlying respiratory conditions. b Clinical monitoring for medically complex patients. c Exacerbation of underlying chronic conditions without alternative explanation. d Includes bulging fontanelle and seizures. e Includes fever, dehydration, chest pain, or gastrointestinal symptoms. f At least one non-SARS-CoV-2 pathogen detected on Respiratory Pathogen Panel Test, Biofire RP2.1. Fifty-three out of fifty-eight patients had Respiratory Pathogen Panel Tests conducted. One patient had 2 viral co-infections. Remaining 5 patients had no viral co-infections detected with Cepheid Xpert Xpress CoV-2/Flu/RSV plus, which tests for SARS-CoV-2, influenza A and B, and RSV.