Table 1.
The list of Genome-wide summary association studies (GWAs) included in the Mendelian randomization (MR) study.
| Exposures | GWAS ID | Consortium | Sample Size | No. of Strongly Related SNPs | Adjustment | Population |
|---|---|---|---|---|---|---|
| Total FA | met-d-Total_FA | UK biobank | 114,999 | 64 | Depression, Worrier, Cholesterol, Smoking, Contraceptives and sclerosing cholangitis | European |
| Saturated FA | met-d-SFA | UK biobank | 114,999 | 55 | ||
| Monounsaturated FA | met-d-MUFA | UK biobank | 114,999 | 66 | ||
| Polyunsaturated FA | met-d-PUFA | UK biobank | 114,999 | 66 | ||
| Omega-3 FA | met-d-Omega_3 | UK biobank | 114,999 | 52 | ||
| Omega-6 FA | met-d-Omega_6 | UK biobank | 114,999 | 63 | ||
| Outcomes | GWAS ID | Consortium | Cases | Control | Population | |
| Crohn’s disease | ieu-a-30 | IIBDGC | 5956 | 14,927 | European | |
| Ulcerative colitis | ieu-a-32 | IIBDGC | 6968 | 20,464 | ||