Table 1.
Cohort characteristics
| Patient characteristics | |
|---|---|
| Cohort, no. (%) | 185 |
| Cambridge University | 65 (35.1%) |
| Mayo Clinic | 120 (64.9%) |
| Male sex, no. (%) | 155 (83.3%) |
| Age, mean (± SD); years | 64.8 (± 11.6) |
| Barrett's length (maximum extent); median (IQR); centimetres | 4 (1–7) |
| Multifocal IND, no. (%) | 42 (22.7%) |
| Persistent IND, no. (%) | 63 (34.1%) |
| Presence of hiatus hernia, no. (%) | 145 (78.4%) |
| Smoking status, no. (%) | |
| Never | 65 (35.1%) |
| Former | 71 (38.4%) |
| Active | 13 (7.0%) |
| Unknown | 36 (19.5%) |
| Sample characteristics | |
| Total number, no. | 216 |
| Cambridge University | 96 (44.4%) |
| Mayo Clinic | 120 (55.6%) |
| Background inflammation*, no. (%) | |
| None | 75 (34.7%) |
| Mild | 98 (45.4%) |
| Moderate | 34 (15.7%) |
| Severe | 0 (0.0%) |
| Missing data | 9 (4.2%) |
| Cause of the BE‐IND diagnosis | |
| Inflammation | 186 (76.9%) |
| Cellular atypia of unknown significance | 43 (17.8%) |
| Technical artefact | 7 (2.9%) |
| Unknown | 6 (2.5%) |
SD, standard deviation; IQR, interquartile range; BE‐IND; Barrett's oesophagus indefinite for dysplasia.
*Mild inflammation: occasional neutrophils within the surface epithelium or crypt epithelium or lamina propria; moderate inflammation: presence of crypt abscesses or scattered collections of neutrophils infiltrate within the surface epithelium; severe inflammation: presence of an ulceration.