TABLE 1.
Characteristics and outcome in all patients, patients with VAP versus patients without VAP
| All patients (n = 171) | VAP (n = 39) | No VAP (n = 132) | p‐value | |
|---|---|---|---|---|
| Age in years, median (IQR) | 66 (53–75) | 67 (53–78) | 65 (53–74) | .593 |
| Female, n (%) | 51 (30) | 7 (18) | 44 (33) | .066 |
| Bystander‐initiated CPR, n (%) | 120 (70) | 28 (72) | 91 (69) | .617 |
| Time to ROSC >20 min, n (%) | 91 (53) | 18 (46) | 69 (52) | .712 |
| Cardiac arrest out of hospital, n (%) | 146 (85) | 32 (82) | 114 (86) | .476 |
| Shockable first monitored rhythm, n (%) | 104 (61) | 25 (64) | 78 (59) | .589 |
| SOFA score on admission, median (IQR) | 10 (9–12) | 11 (9–12) | 10 (8–12) | .024 |
| APACHE II on admission, median (IQR) | 26 (22–31) | 29 (25–33) | 25 (22–30) | .002 |
| Lactate at admission [mg/dl], median (IQR) | 48 (29–85) | 50 (24–71) | 48 (30–89) | .280 |
| CRP max [mg/dl], median (IQR) | 14.8 (8.6–21.7) | 20.4 (14.5–27.2) | 12.3 (7.6–18.9) | .0001 |
| PCT max [µg/L], median (IQR) | 2.8 (0.6–14.1) | 3.3 (1.1–12.3) | 2.2 (0.5–14.4) | .188 |
| Leucocyte count max [G/L], median (IQR) | 17.2 (13.1–22.9) | 18.2 (14.2–23.9) | 16.5 (12.8–22.8) | .171 |
| Mild therapeutic hypothermia, n (%) | 81 (47) | 24 (62) | 57 (43) | .044 |
| Poor outcome at hospital discharge, n (%) | 92 (54) | 25 (64) | 67 (51) | .833 |
| Mortality at hospital discharge, n (%) | 83 (49) | 18 (46) | 65 (49) | .735 |
Abbreviations: VAP, ventilator‐associated pneumonia; IQR, interquartile range; CPR, cardiopulmonary resuscitation; ROSC, return of spontaneous circulation; SOFA, sequential organ failure assessment; APACHE II, acute physiology and chronic health evaluation II; CRP max, C‐reactive protein (maximum within 192 h); PCT max, procalcitonin (maximum within 192 h); Leukocyte count max, leukocyte count (maximum within 192 h).