Table 1.
Physicochemical properties of FA-PAA-Gd2O3 and cRGD/FA-PAA-Gd2O3 nanoparticles.
| Nanoparticle Sample | davg (nm) |
aavg (nm) |
ζ (mV) |
Surface Coating | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| P a | Gd2O3 Nanoparticle | σ b | NNP c | ||||||||
| (wt.%) | (wt.%) | (1/nm2) | |||||||||
| TGA | EA | TGA | EA | TGA | EA | TGA | EA | ||||
| FA-PAA-Gd2O3 | 1.7 | 11.4 | −33.9 | 47.5 | 52.4 | 48.1 | 47.6 | 0.6 | 0.7 | 5.5 | 6.1 |
| cRGD/FA-PAA-Gd2O3 | 1.7 | 13.8 | −16.6 | 51.3 | 56.8 | 45.5 | 43.2 | 0.6 | 0.7 | 5.8 | 6.8 |
a Average ligand surface-coating amount in wt.%. b Grafting density, i.e., average number of ligands (FA-PAA or cRGD/FA-PAA) coating a unit surface area of a nanoparticle. c Average number of ligands coating a nanoparticle.