Table 1. Basic characteristics of industry-sponsored phase III trials conducted during 2008–2019.

Over time development of number of trials, number of participants enrolled and trial duration in months are presented in the table together with corresponding p-values.

Trial characteristics	Trials completed 2008–2011	Trials completed 2012–2015	Trials completed 2016–2019	p-value (Kruskal-Wallis test**)
Number of trials	1965	2031	1976
Total number of participants enrolled	1.245.175	1.249.809	1.156.515	P = 0.1024
Trial duration in months, median (IQR)	22 (13–35)	24 (14–40)	28 (17–47)	P<2.22e-16