TABLE 3.

Probability of second‐infusion ≥50% MMD response based on first‐infusion predictors in the PROMISE‐2 (CM) study

Infusion 1 predictor		Infusion 2 response probability
Percent change in MMDs	Change in HIT‐6 total score	Probability of ≥50% MMD response	95% confidence interval
0%	0	5.9%	3.0%, 11.3%
0%	−6	9.1%	4.8%, 16.8%
0%	−10	12.1%	5.9%, 23.1%
−5%	0	8.0%	4.4%, 13.9%
−5%	−6	12.2%	7.1%, 20.3%
−5%	−10	16.1%	8.7%, 27.7%
−15%	0	14.3%	9.3%, 21.2%
−15%	−6	21.1%	14.7%, 29.5%
−15%	−10	26.9%	17.5%, 39.0%
−25%	0	24.2%	17.6%, 32.4%
−25%	−6	34.0%	26.9%, 41.9%
−25%	−10	41.4%	30.8%, 52.9%
−35%	0	38.1%	28.7%, 48.4%
−35%	−6	49.7%	41.3%, 58.2%
−35%	−10	57.6%	46.3%, 68.2%
−45%	0	54.2%	41.1%, 66.7%
−45%	−6	65.6%	54.8%, 75.0%
−45%	−10	72.3%	60.4%, 81.7%

Abbreviations: CM, chronic migraine; HIT‐6, 6‐item Headache Impact Test; MMD, monthly migraine day.