Table 1.
The seven significant strains of Yarrowia lipolytica selected from the Pareto Front.
| No. of strain | Biomass (WT variation) | β‐carotene production (mmol gDW−1 h−1) | ATP production (WT var. %) (mmol gDW−1 h−1) | NAD(H) production (WT var. %) (mmol gDW−1 h−1) | NADP(H) production (WT var. %) (mmol gDW−1 h−1) | FAD(H2) production (WT var. %) (mmol gDW−1 h−1) | No. of KO |
|---|---|---|---|---|---|---|---|
| WT | 0.011152362 | 0 | 62.68911709 | 11.83086467 | 29.84459341 | 0.128944987 | |
| 1 | 0.01112 (−0.29%) | 0.031725 | 62.7378 (+0.08%) | 11.5504 (0.19) | 29.7883 (−0.19%) | 0.12895 (0%) | 1 |
| 2 | 0.010907 (−2.20%) | 0.22634 | 73.8947 (+17.87%) | 14.7743 (+24.88%) | 32.5591 (+9.10%) | 0.90737 (+603.69%) | 3 |
| 3 | 0.010897 (−2.29%) | 0.22736 | 69.2036 (+10.39%) | 14.7437 (+27.40%) | 32.5388 (+9.03%) | 0.91146 (+606.86%) | 4 |
| 4 | 0.010897 (−2.29%) | 0.22736 | 69.2036 (+10.39%) | 14.7437 (+27.40%) | 32.5388 (+9.03%) | 0.91146 (+606.86%) | 4 |
| 5 | 0.010885 (−2.40%) | 0.22736 | 73.8978 (+17.88%) | 14.776 (+24.89%) | 32.5414 (+9.04%) | 0.91146 (+606.86%) | 5 |
| 6 | 0.010838 (−2.82%) | 0.22737 | 73.7797 (+17.69%) | 14.7484 (+24.66%) | 32.4141 (+8.61%) | 0.91146 (+606.86%) | 6 |
| 7 | 0.010619 (−4.78%) | 0.22637 | 130.8433 (+108.72%) | 25.6254 (+116.60%) | 73.4325 (+146.05%) | 0.90744 (+603.74%) | 6 |
Note: We selected seve strains based on the parameters shown in columns. The first row shows results on wild‐type (WT) strain. Column 1 is the numbering of strains. The second column is the biomass (the total mass of all living material in a specific area, habitat, or region). Other columns from left to right are β‐carotene production (the quantity of β‐carotene produced by strains), adenosine triphosphate (ATP) production, NAD(H) production, NADP(H) production, FAD(H2) production. The last column is the number of knockout genes of strains. We focused primarily on two parameters: biomass and β‐carotene production. Thus, we selected the strains with smaller biomass loss and higher β‐carotene production. The highest values are indicated in bold.