FIGURE 1.

Change from baseline in A, glycated haemoglobin (HbA1c), and B, body weight, by baseline age. Abbreviations: flex, flexibly dosed; OAD, oral antidiabetes drug; SGLT2i, sodium‐glucose cotransporter‐2 inhibitor; SU, sulphonylurea. ^†Including metformin, an SU, an SGLT2i or a thiazolidinedione. Analyses were conducted at the end of treatment on data from the full analysis set using the trial product estimand. The P value indicates a significant treatment‐by‐subgroup interaction with regard to the estimated treatment differences for that trial (two‐sided significance test)