TABLE 1.

Semiquantitative scoring criteria

Host response score	0 (none)	1 (minimal)	2 (mild)	3 (moderate)	4 (severe)
Cell response
Polymorpho‐nuclear cells	0	1–5/hpf*	5–10/hpf	Heavy infiltrate	Packed
Lymphocytes	0	1–5/hpf	5–10/hpf	Heavy infiltrate	Packed
Plasma cells	0	1–5/hpf	5–10/hpf	Heavy infiltrate	Packed
Macrophages	0	1–5/hpf	5–10/hpf	Heavy infiltrate	Packed
Multinucleated giant cells	0	1–2/hpf	3–5/hpf	Heavy infiltrate	Sheets
Necrosis	0	Minimal	Mild	Moderate	Severe
Tissue response
Neo‐vascularization	0	Minimal capillary proliferation, focal, 1–3 buds	Groups of 4–7 capillaries with supporting fibroblastic structures	Broad band capillaries with supporting fibroblastic structures	Extensive band of capillaries with supporting fibroblastic structures
Fibrosis	0	Narrow band	Moderately thick band	Thick band	Extensive band
Fatty infiltration	0	Minimal amount of fat associated with fibrosis	Several layers of fat and fibrosis	Elongated and broad accumulation of fat cells about the implant site	Extensive fat completely surrounding the implant

^*hpf, high‐powered field (40× objective).