Figure 1.

Morphological features and p63 and phosphatase and tensin homologue (PTEN) expression in microglandular hyperplasia. Endocervical microglandular hyperplasia may show a prominent reserve cell layer [A, haematoxylin and eosin (H&E)], although reserve cells are not always conspicuous on H&E‐stained sections. Tightly packed small to medium glands lined by epithelium with subnuclear vacuoles (B, H&E; C, H&E, black arrow) are characteristic features. Linear nuclear immunoreactivity for p63 was seen in subcolumnar reserve cells [D, p63 immunohistochemistry (IHC)]. Mitotic figures were rarely seen in microglandular hyperplasia (MGH) cases (E, H&E, black arrow). Immunohistochemical expression of PTEN was retained in MGH (F, PTEN IHC).