Figure 2.

Morphological features and p63 and phosphatase and tensin homologue (PTEN) expression in endometrial carcinoma. Low‐grade (FIGO grade 1) endometrial endometrioid carcinoma sometimes shows prominent mucinous and/or microglandular features [A,B,C, haematoxylin and eosin (H&E)]. In contrast to microglandular hyperplasia, endometrioid carcinoma typically lacked expression of p63 [D, p63 immunohistochemistry (IHC)]. Mitotic figures, while more often seen in endometrioid carcinoma (E, H&E), could also be seen in microglandular hyperplasia (MGH). Most cases of endometrioid carcinoma showed loss of PTEN expression by immunohistochemistry (F, PTEN IHC).