Table 1.
Key targets prediction of the anti-OP effect of QCT.
| No. | Symbol ID | Protein Name |
|---|---|---|
| 1 | ACTB | Beta-actin |
| 2 | TP53 | Tumor Protein P53 |
| 3 | IL6 | Interleukin 6 |
| 4 | TNF | Tumour Necrosis Factor |
| 5 | ESR1 | Estrogen Receptor 1 |
| 6 | JUN | Jun Proto-Oncogene, AP-1 Transcription Factor Subunit |
| 7 | EGFR | Epidermal Growth Factor Receptor |
| 8 | IL1B | Interleukin 1 Beta |
| 9 | MAPK3 | Mitogen-Activated Protein Kinase 3 |
| 10 | HIF1A | Hypoxia Inducible Factor-1A |
| 11 | HSP90AA1 | Heat Shock Protein 90 Alpha Family Class A Member 1 |
| 12 | MAPK1 | Mitogen-Activated Protein Kinase 1 |
| 13 | NOS3 | Nitric Oxide Synthase 3 |
| 14 | IFNG | Active Interferon Gamma |
| 15 | AR | Androgen Receptor |
| 16 | RelA | NF-Kappa-B Transcription Factor p65 |
| 17 | CCL2 | Monocyte Chemoattractant Protein-1 |
| 18 | ESR2 | Estrogen Receptor Beta |
| 19 | AHR | Aromatic Hydrocarbon Receptor |
| 20 | VCAM1 | Vascular Cell Adhesion Protein 1 |
| 21 | MMP2 | Matrix Metalloproteinase-2 |
| 22 | NFKB1 | Nuclear Factor NF-Kappa-B P105 Subunit |
| 23 | PIK3CA | PI3-Kinase P110 Subunit Alpha |
| 24 | CYP3A4 | Cytochrome P450 Family 3 Subfamily A Member 4 |
| 25 | CYP1A1 | Cytochrome P450 Family 1 Subfamily A Member 1 |
| 26 | PRKCD | Protein Kinase C Delta |
| 27 | HSPB1 | Heat Shock Protein Family B (Small) Member 1 |
| 28 | MMP3 | Matrix Metallopeptidase 3 |
| 29 | CYP19A1 | Cytochrome P450 Family 19 Subfamily A Member 1 |
| 30 | SOD1 | Superoxide Dismutase 1 |