Figure 11.

Cross-section fibrin fiber models and their corresponding stretch modulus. (A) A fiber with uniformly connected protofibrils has a stretch modulus that is independent of diameter, D. (B) A fiber with a bicycle-spokes-like cross-section can have a stretch modulus that decreases as D⁻¹. (C) Based on experimental observations, however, the stretch modulus scales as D^−1.6. This may indicate that the density of connected protofibrils will decrease with increasing fibrin diameter, D, as D^−1.6. Reprinted/adapted with permission from Ref. [160], 2021, Elsevier.