Table 1.

Pharmacokinetic parameters of tangeretin in rat after oral or intravenous administration of tangeretin.

Parameters	Oral (50 mg/kg bw)	Intravenous (5 mg/kg bw)
Tmax (min)	340.00 ± 48.99	–
Cmax (μg/mL)	0.87 ± 0.33	1.07 ± 0.49
t1/2 (min)	342.43 ± 71.27	69.87 ± 15.72
AUC (min · μg/mL)	213.78 ± 80.63	78.85 ± 7.39
AUC/Dose (min/L)	4.28 ± 1.61	15.77 ± 1.48
F (%)	27.11

Data are expressed as mean ± SD from six rats. C_max, peak plasma concentration (μg/mL plasma), t_max; time to reach C_max; t_1/2, elimination half-life; AUC_0–24, area under the concentration–time curve; F, absolute oral bioavailability.