Table 1.
Changes in miRNA expression of T cells during TN → TEFF → TM development. These miRNAs potentially target several genes involved in glycolytic pathway and mitochondrial fission.
| miRNA | Targets |
|---|---|
| miR15a | Glut3, HK1, ALDOA, PKM, PI3K, AKT1, AKT2, Drp1, FIS1 & DNM2 |
| miR15b | Glut3, HK1, ALDOA, PKM, PI3K, MCT1 & Drp1 |
| miR26a | Glut3, TIP1, GAPDH, PGK1, ACAT2, AMPK, MCT1, MFF & MID51 |
| miR26b | Glut3, TIP1, PGK1, LDHA & AMPK |
| miR146a, b | Glut3, ALDOA, PGK1, AMPK, AKT1, MCT4, HIF1A & DNM2 |
| miR101 | TIP1, mTOR, MCT, MFF & DNM2 |
| Let‐7f | Glut3, ALDOA, HK2, PGK1, AMPK, AKT2, MCT4 & MID51 |
| miR142 | Glut3, GPI, PFKM, ALDOA, PI3K, AKT2, MCT2 & HIF1A |
| miR150 | Glut3, GAPDH, PKM, LDHA & MCT1 |
| miR16 | Glut4, HK1, ALDOA, PGK1, PKM, LDHA, AMPK, PI3K, MCT1, MCT2, MCT4, HIF1A & Drp1 |
| miR29a | Glut3, GPI, ALDOA, PI3K, AKT2, MCT1, 2, 4, HIF1A & MID51 |