TABLE 2.

Number of patients with reported adverse events based on CTCAE v4.03 for ADIPemCis

	Total number of patients with AE		Number of patients with AE possibly or probably related to ADI‐PEG20
Adverse event	Grade 1–2	Grade 3–4	Grade 1–2	Grade 3–4
Alopecia	1
Blood bilirubin increase	1
Musculoskeletal Pain	1
Renal impairment	1
Skin ulceration	1		1
Lethargy	2		2
Rash	2		2
Hepatobiliary disorder		1
Portal vein thrombosis		1
Neutropenia		4
Neutropenic sepsis		1
Thrombocytopenia	1	2

Abbreviations: ADI‐PEG, pegylated arginine deiminase; AE, adverse event; CTCAE, Common Terminology Criteria for Adverse Events.