TABLE 3.
Test Characteristics of Tmax Volumes and Tmax Mismatch Ratio
| Sensitivity(95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | |
|---|---|---|---|---|
| Tmax > 9.5 seconds volume ≤ 111.6 ml | 0.76 (0.70–0.81) | 0.82 (0.74–0.88) | 0.89 (0.84–0.92) | 0.64 (0.59–0.69) |
| Tmax > 16 seconds volume ≤ 67.0 ml | 0.91 (0.87–0.94) | 0.73 (0.64–0.80) | 0.86 (0.83–0.89) | 0.81 (0.74–0.87) |
| Tmax mismatch volume ≤ 58.3 ml | 0.63 (0.57–0.69) | 0.70 (0.61–0.77) | 0.80 (0–75‐0.84) | 0.50 (0.45–0.55) |
| Tmax mismatch ratio > 2.5 | 0.70 (0.64–0.76) | 0.79 (0.71–0.85) | 0.86 (0.82–0.90) | 0.58 (0.53–0.63) |
CI = confidence interval; NPV = negative predictive value; PPV = positive predictive value; Tmax = time to maximum concentration. Outcome of interest: modified Rankin Scale 0 to 2 at 90 days.