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. 2022 Apr 29;61(26):e202200269. doi: 10.1002/anie.202200269

Figure 2.

Figure 2

Functional activity of morphine, fentanyl, PZM21 and FH210 at the μOR. A) G‐protein signaling measured by IP accumulation assay in cells transfected with the chimeric G protein Gqi. B), C) β‐arrestin‐2 recruitment measured by PathHunter assay, with (C) and without (B) GRK2 co‐transfection. D) Gi/o/z subtypes activation measured by BRET‐based assay. [14]