Figure 2.

Association between p16 and αSMA expression and fibrous tissue using serial 10 µm sections cut from the same biopsy. High hepatocyte p16 expression was closely associated with increased hepatic stellate cell activation (shown by high αSMA expression) and thick fibrous tissue (panel A), and low p16 expression was closely associated with low αSMA expression and thin fibrous tissue (panel B). Magnification is at 10× with insets for p16 expression is shown at magnification 40×. Scale bar length is 100 µm at 10× magnification.