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. 2022 Jul 11;23(14):7651. doi: 10.3390/ijms23147651

Figure 3.

Figure 3

The endo-lysosomal compartments are altered in COL6-RD patient-derived fibroblasts. (A) Representative STED images of Lamp1- and (B) EEA1-positive organelles labelled in control- and COL6-RD patient-derived fibroblasts and in CRISPR-treated COL6-RD patient-derived fibroblasts. (C) Lamp1- and (E) EEA1-positive organelles density, together with the area of (D) Lamp1- and (F) EEA1-positive organelles was quantified. Data are expressed as the mean ± SEM; n = 3; independent primary cell preparations were used for all panels. * p < 0.05; one-way ANOVA/Bonferroni’s multiple comparison test. Scale bar 5 µm.