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. 2022 Jul 16;14(7):1482. doi: 10.3390/pharmaceutics14071482

Table 5.

Evaluation of encapsulated nucleic acids.

Objective Method Ref.
RNA or DNA quantification UV-Vis spectrophotometry [93,96,97]
Fluorescence spectrophotometry [79]
Target-specific fluorescence detection [93,96]
Capillary electrophoresis separation of fluorescently labelled nucleic acids [93,96]
qRT-PCR [97,98,99]
Gel electrophoresis on 1% agarose gel [87]
miRNA expression profiles Provides 100% coverage of the miRNAs in the miRBase database [96]

qRT-PCR—Real-time polymerase chain reaction.