Table 4.

The relationship between CCSCs subtypes and measuring outcome. * Multivariate analysis.

Study			Preoperative Analysis
	Outcomes		Fan, 2011 [34]	Liu, 2013 [35]	Guo, 2018 [36]	Lei, 2021 [31]
RFS DFS TTR	HR			7.15	3.127
	95% CI			2.99–17.09	1.360–7.190
	p-value			0.0001	0.007
	RR		4.175
	95% CI		2.143–8.133
	p-value		<0.0001
	Median	pos	6
		neg	46.5
	p-value		<0.0001
	RR		4.175
	95% CI		2.143–8.133
	p value		<0.0001
ER	HR					2.33 *
	95% CI					1.476–3.679
	p-value					0.000282
OS	HR			2.28
	95% CI			0.95–7.82
	p-value			0.062
	RR		4.735
	95% CI		1.709–13.12
	p-value		0.003
	Median	pos	30
		neg	>57.1
	p-value		0.0005