Table 2. Modelling results of educational attainment in the UK Biobank.
| Full sample | ||||||
|---|---|---|---|---|---|---|
| Unweighted PRS | Weighted PRS | |||||
| Estimate | Std Error | p-value | Estimate | Std Error | p-value | |
| Offspring effect | 0.026 | 0.005 | 3.18 × 10 -7 | 2.474 | 0.485 | 3.40 × 10 -7 |
| Prenatal maternal effect | 0.027 | 0.011 | 0.013 | 1.722 | 0.703 | 0.014 |
| Postnatal maternal effect | –0.006 | 0.008 | 0.484 | –0.288 | 0.514 | 0.575 |
| Postnatal paternal effect | 0.018 | 0.007 | 0.006 | 1.233 | 0.678 | 0.069 |
| Excluding adopted individuals with breastfeeding information | ||||||
| Unweighted PRS | Weighted PRS | |||||
| Estimate | Std Error | p-value | Estimate | Std Error | p-value | |
| Offspring effect | 0.025 | 0.005 | 5.52 × 10–7 | 2.441 | 0.372 | 5.15 × 10–11 |
| Prenatal maternal effect | 0.017 | 0.012 | 0.140 | 0.909 | 0.705 | 0.197 |
| Postnatal maternal effect | 0.004 | 0.009 | 0.682 | 0.549 | 0.595 | 0.357 |
| Postnatal paternal effect | 0.019 | 0.007 | 0.005 | 1.273 | 0.552 | 0.021 |
PRS: polygenic risk score constructed using 1,267 SNPs from Lee et al., 2018; Std Error: standard error.