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Mitochondrial damage and alteration of energy metabolism in GEM-resistant human PDAC cases. MYCC mRNA expression and TFAM protein levels were examined in three GEM-sensitive and four GEM-resistant cases. Error bars represent standard error from patients. GEM—gemcitabine; TFAM—mitochondrial transcription factor A; ACTB—beta-actin; S—GEM sensitive; R—GEM resistant.
