Table 1.
Clinical data from the positive patients in CSF samples.
| ID | Gender, Age |
Clinical Syndrome | Signs and Symptoms | CSF Characteristics | Other Observations | Diagnostic Test |
|---|---|---|---|---|---|---|
| 144 | Male, 61 | Meningitis | Fever, myalgia, lethargy | Leukocytes 4 cells/mm3, lymphocytes 88%, neutrophils 2%, protein 44 mg/dL, glucose 90 mg/dL, culture negative | Leukopenia (2580 leukocytes/mm3); comorbidity: HIV infection | ZIKVElisa IgM positive |
| 177 | Female, 71 | Brain bleeding | Headache | Leukocytes 11 cells/mm3, lymphocytes 67%, neutrophils 10%, protein 90 mg/dL, glucose 64 mg/dL, culture negative | No coagulation disorders detected | ZIKVPCR positive |
| 194 | Male, 74 | Encephalitis | Lethargy, mental confusion and decreased consciousness awareness | Leukocytes 17 cells/mm3, lymphocytes 67%, neutrophils 23%, protein 161 mg/dL, glucose 21 mg/dL, culture negative | ZIKVPCR positive | |
| 248 | Female, 59 | Brain bleeding | Fever, náusea, irritability, respiratory distress | Leukocytes 89 cells/mm3, lymphocytes 74%, neutrophils 6%, protein 71 mg/dL, glucose 82 mg/dL, culture negative | ZIKVPCR positive | |
| 253 | Male, 56 | Meningitis | Fever, lethargy, dyspnea, mental confusion | Leukocytes 39 cells/mm3, lymphocytes 50%, neutrophils 38%, protein 98 mg/dL, glucose 41 mg/dL, culture negative | Comorbidity: HIV infection | ZIKVPCR positive |
| 257 | Female, 51 | Demyelinating polyneurophaty | Myalgia, peripheral facial palsy, ataxy, decreased lower limbs strength | Leukocytes 11 cells/mm3, lymphocytes 95%, neutrophils 5%, protein 187 mg/dL, glucose 47 mg/dL, culture negative | Comorbidity: HIV infection | ZIKVPCR positive |
| 272 | Male, 18 | Meningitis | Fever, headache | Leukocytes 29 cells/mm3, lymphocytes 76%, neutrophils 6%, protein 81 mg/dL, glucose 79 mg/dL, culture negative | Comorbidity: Hyper IgD syndrome | ZIKVPCR positive |
| 04 | Female, 50 | Encephalitis | Aphasia, mental confusion, convulsive crisis and decreased consciousness awareness | Leukocytes 2 cells/mm3, lymphocytes 80%, neutrophils 8%, protein 91 mg/dL, glucose 69 mg/dL, culture negative | DENVPCR positive | |
| 06 | Female, 65 | Encephalitis | Speech difficulty, drowsiness, decreased lower limbs strength | Leukocytes 1 cells/mm3, lymphocytes 85%, neutrophils 5%, protein 44 mg/dL, glucose 251 mg/dL, culture negative | DENVPCR positive |
CSF: cerebrospinal fluid; reference values: Leukocytes ≤ 3 cells/mm3, lymphocytes ≥ 90%, neutrophils ≤ 10%, protein ≤ 40 mg/dL, glucose ≥ 2/3 serum level, culture negative.