Table 7.
Superiority of Interceptor® G2 over Interceptor® was estimated by comparing the membrane assay to the gold standard assay with pyrethroid-resistant mosquitoes. The difference in the odds of mosquito at 72-h (M72) and blood feeding success (BFS) for resistant Anopheles arabiensis measuring the superiority of Interceptor® G2 and Interceptor® with the gold standard with 100-rabbit compared to 50-membrane bioassays *.
| Treatment | 100-Rabbit | 50-Membrane | ||||||
|---|---|---|---|---|---|---|---|---|
| BFS | M72 | BFS | M72 | |||||
| OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | OR (95% CI) | p-Value | |
| Overall | ||||||||
| Interceptor® | 1 | 1 | 1 | 1 | ||||
| Interceptor® G2 | 1.76 (1.47–2.10) | <0.001 | 1.23 (1.10–1.38) | <0.001 | 1.87 (1.05–3.33) | 0.033 | 1.79 (1.50–2.14) | <0.001 |
| Unwashed | ||||||||
| Interceptor® | 1 | 1 | 1 | 1 | ||||
| Interceptor® G2 | 1.64 (1.28–2.09) | <0.001 | 1.15 (0.98–1.35) | 0.094 | 2.34 (1.11–4.93) | 0.025 | 1.81 (1.43–2.29) | <0.001 |
| Washed 20× | ||||||||
| Interceptor® | 1 | 1 | 1 | 1 | ||||
| Interceptor® G2 | 1.90 (1.47–2.45) | <0.001 | 1.31 (1.12–1.54) | 0.001 | 1.26 (0.49–3.20) | 0.634 | 1.82 (1.39–2.37) | <0.001 |
* For the gold standard, 100-mosquitoes with rabbit and 50-mosquito with 2 Hemotek® membrane feeders augmented with worn socks were used in the WHO tunnel bioassay, adjusted for net type and condition.