Table 6.
APOE genotype and allele frequencies in patients with ON with MS and without MS.
| Genotype, Allele | ON without MS (n = 46) | Control Group (n = 583) | p-Value | ON with MS (n = 30) |
Control Group (n = 583) |
p-Value |
|---|---|---|---|---|---|---|
| APOE ε2/ε2, n (%) | 0 (0) | 3 (0.5) | - | 0 (0) | 3 (0.5) | - |
| APOE ε2/ε3, n (%) | 7 (15.2) | 84 (14.4) | 0.881 | 4 (13.3) | 84 (14.4) | 0.870 |
| APOE ε2/ε4, n (%) | 1 (2.2) | 17 (2.9) | 0.771 | 0 (0) | 17 (2.9) | - |
| APOE ε3/ε3, n (%) | 32 (69.6) | 387 (66.4) | 0.659 | 22 (73.3) | 387 (66.4) | 0.431 |
| APOE ε3/ε4, n (%) | 6 (13.0) | 85 (14.6) | 0.776 | 4 (13.3) | 85 (14.6) | 0.850 |
| APOE ε4/ε4, n (%) | 0 (0) | 7 (1.2) | - | 0 (0) | 7 (1.2) | - |
| ε2 allele, n (%) | 8 (8.7) | 107 (9.2) | 0.878 | 4 (7.1) | 107 (9.2) | 0.605 |
| ε3 allele, n (%) | 77 (83.7) | 943 (80.9) | 0.176 | 48 (85.8) | 943 (80.9) | 0.533 |
| ε4 allele, n (%) | 7 (7.6) | 116 (9.9) | 0.467 | 4 (7.1) | 116 (9.9) | 0.491 |