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. 2022 Jul 16;14(14):3459. doi: 10.3390/cancers14143459

Figure 1.

Figure 1

AKRO-QC-ICG accumulates in lysosomes and becomes fluorescent in the human BCa cells in vitro. Representative live cell fluorescence microscopy images of the human breast MDA-MB-486 cancer cell monolayer incubated for 30 min with 1 μM of quenched substrates followed by washout. ICG fluorescence of probe is false-colored red, lysotracker (lysosome selective stain) is false colored green, blue is DAPI (nuclear stain), and yellow/orange corresponds to lysosome/ICG co-localization. Magnification—100× with immersion (Leica-DM4000B). Scale bar—10 μm.