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. 2022 Apr 26;20(7):1535–1549. doi: 10.1111/jth.15734

FIGURE 7.

FIGURE 7

Platelet‐inspired nanomedicine approaches in thrombosis and thromboinflammation: Therapeutic agents can be modified directly with targeting ligands (e.g. antibodies, antibody fragments, peptides etc.) that bind to clot‐specific entities (e.g. activated platelets, fibrin, leukocytes etc.), or they can be packaged with nanoparticles surface‐decorated with such ligand motifs; Release of surface‐immobilized or encapsulated drug from the particles can be triggered by various endogenous (e.g. enzyme, shear) or external (e.g. magnetic, laser, ultrasound) stimuli