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. 2022 May 2;17(12):e202200115. doi: 10.1002/cmdc.202200115

Figure 2.

Figure 2

Examples of cytochrome P450‐catalysed hydroxylations for HDM synthesis. A) HDM synthesis of 5‐ESO (2) using P450BM3 mutants. B) HDM synthesis of 5‐hydroxydiclofenac (4) using self‐sufficient cytochrome P450RhF.