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. 2022 Jul 12;23(14):7709. doi: 10.3390/ijms23147709

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Cardiomyocyte size and perivascular fibrosis correlation with disease progression. (A) C57Bl/6J wild-type mice treated with Angiotensin II (AngII; 0.8 mg/kg/d) for up to 14 d. Correlation of cardiomyocyte cross-sectional area with perivascular fibrosis (as a percentage of total area). (B) Human post-mortem cardiac tissue with hypertension and hypertensive heart disease. Correlation of cardiomyocyte cross-sectional area with perivascular fibrosis (as a percentage of total area). Stats: Pearson correlation, with 2-tailed test reporting p-values.