| TME | Tumor microenvironment |
| ICI | Immune checkpoint inhibitors |
| CTLA-4 | Cytotoxic T Lymphocyte Antigen 4 |
| PD1 | Programmed cell Death 1 |
| PD-L1 | PD1 Ligand 1 |
| ECM | Extracellular Matrix |
| US FDA | United States Food and Drug Administration |
| NSCLC | Non-Small-Cell Lung Cancer |
| MHC | Major Histocompatibility Complex |
| Mut/Mb | Mutations per coding genomic region analyzed |
| TMB | Tumor Mutational Burden |
| TMB-H | High Tumor Mutational Burden |
| TCGA | The Cancer Genome Atlas |
| WES | Whole Exome Sequencing |
| NGS | Next-Generation-Sequencing |
| F1CDx | FoundationOne CDx |
| MSK-IMPACT | Memorial Sloan Kettering Cancer Center’s Integrated Mutation Profiling of Actionable Cancer Targets |
| FoundationACT | Assay for Circulation Tumor DNA |
| MSI | Microsatellite Instability |
| dMMR | Defective DNA mismatch repair |
| MSI-H | High MSI |
| GEP | Gene Expression Profiling |
| cDNA | Complementary DNA |
| RNA-seq | RNA Sequencing |
| DGE | Differential Gene Expression |
| GSEA | Gene Set Enrichment Analysis |
| WGCNA | Weighted Gene Co-expression Network Analysis |
| TIS | Tumor Inflammation Signature |
| FFPE | Formalin-Fixed Paraffin-Embedded |
| mRNA | Messenger RNA |
| scRNA-seq | Single Cell RNA-seq |
| DEPArray | Di-Electro-Phoretic Array |
| STTs | Spatial Transcriptomic Technologies |
| DSP | Digital Spatial Profiling |
| ROI | Regions of Interest |
| STEREO-seq | SpaTial Enhanced REsolution Omics-sequencing |
| DNB | DNA nanoball |
| PDAC | Pancreatic Ductal Adenocarcinoma |
| CSCC | Cervical Squamous Cell Carcinoma |
| CAFs | Cancer-Associated Fibroblasts |
| HPV | Human Papillomavirus |
| TGF-β | Transforming Growth Factor β |