Skip to main content
. 2022 Jul 5;10(7):1078. doi: 10.3390/vaccines10071078

Figure 3.

Figure 3

Antigen concentrations present in the DTaP vaccine and control vaccine (A) and the concentration of the missing antigen in its corresponding control DTaP vaccine (B). The nominal antigen concentrations and the CV of the analysis are depicted at the top of the graph. The used signature peptides are shown on the X-axis. To determine antigen concentration in the DTaP vaccine, 100 pmol of each internal standard peptide was added to 100 µL vaccine and digested with 0.33 µg Asp-N. (A): vaccine A (n = 36 for each antigen and signature peptide combination, except for pep_FHA_01 (n = 31) and pep_PTd_01 (n = 33)); (B): experimental (control) vaccines in which the quantified antigen was missing (n = 9 per signature peptide).