Figure 3.

α Diversity by Chao1 of young and old mice that underwent CLP-DCS was analyzed for each sex and demonstrates that (A) young male mice do not have alterations in the α diversity of their intestinal microbiota after CLP-DCS but their old male counterparts do (B; FDR, 0.002). Similarly, young female mice that undergo CLP-DCS have stable α diversity after CLP-DCS (C), but old female mice were noted to have decreased α diversity over time after CLP-DCS (D; FDR, <0.001).