Figure 16.

Differential expression of enzymes involved in glycolysis, pentose phosphate pathway, TCA cycle and oxidative phosphorylation in RA CD8⁺ Tem cells. Solid red UP arrows indicate upregulation/increased activity. Solid blue down arrows indicate downregulation. Light red arrows indicate statistically significant upregulation with low read counts. Pathways where the overall effect of differential regulation on the activity of the pathway is ambiguous are marked by a question mark. PPP—pentose phosphate pathway; G6P—glucose-6-phosphate; F6P—fructose-6-phosphate; GA3P—glyceraldehyde-3-phosphate.