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Upregulated and downregulated genes of treated RA compared with untreated RA samples of T cell subsets.
| Cell Type | Methotrexate | Infliximab | Tocilizumab | |||
|---|---|---|---|---|---|---|
| UP | DOWN | UP | DOWN | UP | DOWN | |
| CD4+ Tn | 1 | 9 | 12 | 4 | 4 | 20 |
| CD4+ Tcm | 1 | 1 | 1 | 8 | 2 | 4 |
| CD4+ Tem | 2 | 2 | 0 | 3 | 4 | 6 |
| CD8+ Tn | 16 | 51 | 0 | 26 | 19 | 711 |
| CD8+ Tcm | 3 | 6 | 2 | 3 | 3 | 3 |
| CD8+ Tem | 26 | 13 | 4 | 7 | 91 | 1047 |
| CD8+ Temra | 45 | 266 | 35 | 130 | 12 | 59 |
