Figure 3.

Effect of NHEJi in proliferation and cell viability. (A) Cell proliferation after treatment with the indicated doses of KU-57788, NU-7026, or SCR7 pyrazine for 24, 48, and 72 h. Data are the mean of three independent experiments. (B) Cell viability after the treatment with the indicated doses of KU-57788 and NU-7026. The percentage of live cells was determined by Annexin V/PI staining. Data are the mean of at least three independent experiments. Error bars represent the SD. Differences between the results obtained from treated and nontreated cells were assessed for statistical significance using Student’s unpaired two-tailed t-test (** p < 0.01 and * p < 0.05 compared to untreated cells).