Table 5.
Coverage breadth (%) of sequencing reads of samples D14IT15.2 and D14IT20 mapped to genes involved in the biotin synthesis in the genome of Francisella persica and Midichloria mitochondrii, indicating an intact biotin synthesis pathway of Midichloria and a disrupted biotin synthesis pathway of Francisella-like endosymbionts detected in the tick species Hyalomma rufipes.
| Enriched | Non-Enriched | ||||
|---|---|---|---|---|---|
| Homolog in Midichloria/Francisella Genomes | D14IT15.2 | D14IT20 | D14IT15.2 | D14IT20 | Genes Involved in the Biotin Synthesis |
| lcl|NC_015722.1_cds_WP_013950979.1_473 [M. mitochondrii] | 0 * | 0 | 100 | 100 | bioA |
| lcl|NC_015722.1_cds_WP_013950663.1_135 [M. mitochondrii] | 13.4 | 0 | 99.0 | 98.6 | bioB |
| lcl|NC_015722.1_cds_WP_237697388.1_131 [M. mitochondrii] | 0 | 0 | 99.7 | 95.4 | bioC |
| lcl|NC_015722.1_cds_WP_013950658.1_130 [M. mitochondrii] | 0 | 0 | 93.7 | 93.5 | bioD |
| lcl|NC_015722.1_cds_WP_237697389.1_134 [M. mitochondrii] | 0 | 0 | 88.0 | 87.9 | bioF |
| lcl|NZ_CP013022.1_cds_WP_064461154.1_1224 [F. persica] | 21.5 | 19.7 | 0 | 0 | Homolog to bioA in F. tularensis (FTT_0938) |
| lcl|NZ_CP013022.1_cds_WP_064461748.1_1225 [F. persica] | 100 | 100 | 0 | 0 | Homolog to bioB in F. tularensis (FTT_0937c) |
| lcl|NZ_CP013022.1_cds_WP_064461156.1_1227 [F. persica] | 76.3 | 74.3 | 0 | 0 | Homolog to bioC in F. tularensis (FTT_0935c) |
| lcl|NZ_CP013022.1_cds_WP_064461157.1_1228 [F. persica] | 99.3 | 99.3 | 0 | 32.5 | Homolog to bioD in F. tularensis (FTT_0934c) |
| lcl|NZ_CP013022.1_cds_WP_064461155.1_1226 [F. persica] | 63.3 | 64.4 | 0 | 0 | Homolog to bioF in F. tularensis (FTT_0936c) |
| Reads deposited to NCBI sequence read archive | SRR16203935 | SRR16203936 | SRR16203939 | SRR16203940 | |
* Values are color-coded and the highest values are indicated by bright red.