Table 5.
Frequency of self-reported adverse events by age group among 6654 patients.
| Symptoms | Age (Years) | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 10 to 20 | 20 to 30 | 30 to 40 | 40 to 50 | 50 to 60 | 60 to 70 | 70 to 80 | 80 to 90 | 90 to 100 | Total | |||||||||||
| n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | n | ||
| Mild self-reported ESAVIs | Joint pain | 15 | 0.9% | 377 | 23.3% | 541 | 33.4% | 359 | 22.2% | 218 | 13.5% | 89 | 5.5% | 16 | 1.0% | 2 | 0.1% | 2 | 0.1% | 1619 |
| Headache | 90 | 2.6% | 907 | 25.9% | 1067 | 30.5% | 721 | 20.6% | 476 | 13.6% | 192 | 5.5% | 35 | 1.0% | 13 | 0.4% | 1 | 0.0% | 3502 | |
| Muscle pain | 59 | 2.0% | 763 | 26.3% | 899 | 31.0% | 587 | 20.3% | 389 | 13.4% | 157 | 5.4% | 32 | 1.1% | 9 | 0.3% | 2 | 0.1% | 2897 | |
| Pain or swelling at the injection site | 100 | 2.2% | 1162 | 25.8% | 1388 | 30.8% | 959 | 21.3% | 574 | 12.8% | 259 | 5.8% | 42 | 0.9% | 11 | 0.2% | 5 | 0.1% | 4500 | |
| Fatigue or tiredness | 100 | 3.0% | 949 | 28.7% | 1045 | 31.6% | 645 | 19.5% | 358 | 10.8% | 140 | 4.2% | 45 | 1.4% | 20 | 0.6% | 0 | 0.0% | 3302 | |
| Shaking chills | 35 | 1.7% | 605 | 28.8% | 695 | 33.1% | 425 | 20.2% | 244 | 11.6% | 77 | 3.7% | 16 | 0.8% | 2 | 0.1% | 1 | 0.0% | 2100 | |
| Mild/low grade fever (37.1–38 °C) | 16 | 1.1% | 453 | 30.8% | 488 | 33.2% | 288 | 19.6% | 153 | 10.4% | 57 | 3.9% | 12 | 0.8% | 2 | 0.1% | 0 | 0.0% | 1469 | |
| General Discomfort | 67 | 2.4% | 785 | 28.1% | 884 | 31.6% | 564 | 20.2% | 320 | 11.5% | 130 | 4.7% | 31 | 1.1% | 11 | 0.4% | 2 | 0.1% | 2794 | |
| Gastrointestinal Discomfort | 5 | 0.9% | 133 | 25.1% | 148 | 28.0% | 133 | 25.1% | 68 | 12.9% | 35 | 6.6% | 5 | 0.9% | 1 | 0.2% | 1 | 0.2% | 529 | |
| Urinary Discomfort | 0 | 0.0% | 29 | 28.4% | 33 | 32.4% | 23 | 22.5% | 12 | 11.8% | 4 | 3.9% | 0 | 0.0% | 0 | 0.0% | 1 | 1.0% | 102 | |
| Moderate self-reported ESAVIs | Diarrhea | 8 | 2.0% | 84 | 20.8% | 121 | 30.0% | 95 | 23.5% | 52 | 12.9% | 33 | 8.2% | 8 | 2.0% | 2 | 0.5% | 1 | 0.2% | 404 |
| Skin rash | 5 | 3.1% | 39 | 24.5% | 52 | 32.7% | 28 | 17.6% | 21 | 13.2% | 13 | 8.2% | 1 | 0.6% | 0 | 0.0% | 0 | 0.0% | 159 | |
| Fever (>38 °C) | 16 | 1.9% | 261 | 31.5% | 245 | 29.6% | 164 | 19.8% | 101 | 12.2% | 33 | 4.0% | 7 | 0.8% | 2 | 0.2% | 0 | 0.0% | 829 | |
| Swollen Glands | 10 | 2.4% | 119 | 28.1% | 123 | 29.0% | 99 | 23.3% | 58 | 13.7% | 15 | 3.5% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 424 | |
| Nausea | 18 | 2.5% | 218 | 29.8% | 225 | 30.8% | 145 | 19.8% | 86 | 11.8% | 27 | 3.7% | 10 | 1.4% | 1 | 0.1% | 1 | 0.1% | 731 | |
| Pruritus (Itching) | 12 | 4.0% | 86 | 28.6% | 74 | 24.6% | 77 | 25.6% | 36 | 12.0% | 16 | 5.3% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 301 | |
| Vomit | 4 | 2.9% | 50 | 36.0% | 38 | 27.3% | 23 | 16.5% | 18 | 12.9% | 6 | 4.3% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 139 | |
| Severe self-reported ESAVIs | Anaphylaxis | 1 | 11.1% | 4 | 44.4% | 2 | 22.2% | 1 | 11.1% | 1 | 11.1% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 9 |
| Tachycardia | 6 | 2.3% | 61 | 23.7% | 59 | 23.0% | 67 | 26.1% | 37 | 14.4% | 17 | 6.6% | 9 | 3.5% | 1 | 0.4% | 0 | 0.0% | 257 | |
| Guillain Barre sd. | 0 | 0.0% | 1 | 10.0% | 3 | 30.0% | 4 | 40.0% | 1 | 10.0% | 1 | 10.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 10 | |
| Facial swelling | 1 | 3.8% | 3 | 11.5% | 11 | 42.3% | 3 | 11.5% | 6 | 23.1% | 1 | 3.8% | 1 | 3.8% | 0 | 0.0% | 0 | 0.0% | 26 | |
| High Blood Pressure | 0 | 0.0% | 9 | 10.3% | 16 | 18.4% | 25 | 28.7% | 22 | 25.3% | 12 | 13.8% | 2 | 2.3% | 1 | 1.1% | 0 | 0.0% | 87 | |
| Transverse Myelitis | 0 | 0.0% | 2 | 100.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 2 | |
| Facial Paralysis | 0 | 0.0% | 2 | 18.2% | 2 | 18.2% | 4 | 36.4% | 3 | 27.3% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 11 | |
| Coagulation Disorders | 0 | 0.0% | 5 | 15.6% | 9 | 28.1% | 12 | 37.5% | 2 | 6.3% | 2 | 6.3% | 2 | 6.3% | 0 | 0.0% | 0 | 0.0% | 32 | |
| Total | 568 | 2.2% | 7107 | 27.1% | 8168 | 31.1% | 5451 | 20.8% | 3256 | 12.4% | 1316 | 5.0% | 274 | 1.0% | 78 | 0.3% | 17 | 0.1% | 26,235 | |