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Inhibition of A549 tumor growth by dsVDUP1-834 treatment in nude mouse xenograft model. Specific pathogen-free BALB/c nude mice (n = 5) were implanted subcutaneously with A549 cells (9 × 106 cells/mouse) and treated with vehicle, dsCon (5 mg/kg) and dsVDUP1-834 (5 mg/kg). Tumor volumes are measured, and data are represented as mean ± S.D (n = 5). * denotes that the response is significantly different from vehicle-treated group as determined by Dunnett’s t-test at p < 0.05.
